产品货号：
Z10026
中文名称：
AATF抗体
英文名称：
Anti-AATF Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AATF Antibody |
| 指标别名 | AATF;CHE 1;CHE1;DED;Protein AATF;Rb binding protein Che 1;Traube |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | AATF |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | AATF antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus of human AATF.The immunogen is located within the last 50 amino acids of AATF. |
| 计算分子量 | 63kDa |
| 成分 | AATF Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | AATF Antibody is immunoaffinity purified IgG. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | AATF (apoptosis antagonizing transcription factor) was initially discovered as an interaction partner of ZIP kinase (ZIPK),a member of death-associated protein (DAP) kinase family of pro-apoptotic serine/threonine kinases.AATF is a phosphoprotein containing an acidic region and a putative leucine zipper domain and nuclear localization signal,features which are typical of transcription factors.AATF inhibits the ZIPK-mediated pro-apoptotic pathway and may activate other anti-apoptotic pathways.Recently,it has also been shown to protect neural cells against oxidative damage induced by amyloid b-peptide and to inhibit aberrant production of the beta-peptide by interacting with Par-4 (prostate apoptosis response-4),another pro-apoptotic leucine zipper protein that is associated with neuronal degeneration in Alzheimer's disease (AD),suggesting that AATF may have potential therapeutic applications in both familial and sporadic forms of AD. |
| Uniprot ID | Q9NY61 |
| 基因名全称 | Apoptosis antagonizing transcription factor |
| 蛋白名全称 | Apoptosis antagonizing transcription factor |
| 推荐稀释比 | AATF antibody can be used for the detection of AATF by Western blot at 0.5 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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